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Case Reports in Medicine
Volume 2018, Article ID 8057045, 4 pages
Case Report

A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease

1Department of Medicine, Woodlands Health Campus (WHC), Singapore
2Department of Haematology, Tan Tock Seng Hospital, Singapore

Correspondence should be addressed to Veeraraghavan Meyyur Aravamudan; gs.chw@ruyyem_navahgarareev_nadumavara

Received 30 July 2018; Revised 27 October 2018; Accepted 6 December 2018; Published 24 December 2018

Academic Editor: Walter Zidek

Copyright © 2018 Veeraraghavan Meyyur Aravamudan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature.