Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies
Figure 1
Glomeruli from the renal biopsy. (a) Cellular destructive crescent with discontinuities in Bowman’s capsule (arrow). The adjacent interstitium had edema and a mononuclear leukocytic infiltrate. Periodic acid-Schiff ×250. (b) Immunofluorescence showing strong (3-4+) linear IgG staining along capillary walls. The capillary walls are disrupted focally due to crescent formation ×250. (c) Broken glomerular capillary wall (arrow) associated with a cellular crescent. There are no capillary wall electron dense deposits ×10,000.
