Case Report
Corticosteroids in Patients with IgA Nephropathy and Severe Chronic Renal Damage
Table 1
Baseline clinical and histological characteristics of the four patients.
| Patient | IE | RM | CS | LA |
| Age (years) | 55 | 54 | 46 | 42 | Body mass index (kg/m2) | 31 | 26 | 28 | 27 | Systolic BP (mmHg) | 162 | 155 | 130 | 123 | Diastolic BP (mmHg) | 92 | 90 | 80 | 80 | Serum creatinine (mg/dL) | 3.0 | 3.5 | 3.9 | 3.2 | Proteinuria (g/day) | 5.1 | 3.4 | 4.0 | 1.8 | eGFR (using MDRD) | 26.2 | 19.5 | 17.8 | 22.7 | Treatment with ACEI | No | Yes | Yes | No | Treatment with ARB | Yes | No | No | Yes | Glomeruli with global sclerosis | 50% | 50% | 43% | 33% | Tubular atrophy | 25–50% | >50% | >50% | 25–50% | Interstitial fibrosis | Moderate | Severe | Severe | Moderate | Arterial sclerosis | Severe | Severe | Not Eval. | Moderate |
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