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Case Reports in Nephrology
Volume 2012, Article ID 406406, 4 pages
Case Report

Kidney Transplant in a 26-Year-Old Nigerian Patient with Sickle Cell Nephropathy

1Renal Unit, Department of Medicine, Enugu State University Teaching Hospital, Enugu, Nigeria
2Renal Unit, Department of Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria

Received 12 November 2012; Accepted 29 November 2012

Academic Editors: A. K. Saxena and A. Segarra

Copyright © 2012 U. H. Okafor et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Sickle cell nephropathy (SCN) is a common complication of sickle cell disease (SCD). It has variable presentation, ranging from hyposthenuria to end-stage renal disease (ESRD). Management of ESRD in SCD patients is froth with multiple challenges which has potential to impact negatively the outcome of the patient. Kidney transplant is the preferred renal replacement therapy in these patients. The objective of this case study is to report kidney transplant in a Nigerian young man with sickle cell nephropathy and to highlight the outcome and the challenges to kidney transplant in this patient. The index case is a 26-years-old sickle cell disease patient with ESRD complicated with cardiovascular, pulmonary, immunological, and infective challenges. These conditions were controlled, and the patient had a successful live-related kidney transplant. Kidney transplant is a viable option for sickle cell disease patients with ESRD.