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Case Reports in Nephrology
Volume 2013, Article ID 124604, 3 pages
http://dx.doi.org/10.1155/2013/124604
Case Report

Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature

1Department of Internal Medicine, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37615, USA
2Department of Nephrology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37615, USA
3Department of Pathology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37615, USA

Received 19 February 2013; Accepted 17 April 2013

Academic Editors: C.-T. Lee, G. V. R. Prasad, A. K. Saxena, and A. Segarra

Copyright © 2013 Dhara Chaudhari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Orlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat. Herein we report a patient presenting with acute renal failure which improved minimal with intravenous hydration. She was found to have oxalate crystals on renal biopsy. Patient admitted orlistat use over the counter for weight reduction on further questioning. The purpose of this case review is to increase awareness among patients since they are more focused on losing weight. This case also calls for the provider attention to educate patients regarding side effects of orlistat because of easy availability of orlistat over the counter.