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Case Reports in Nephrology
Volume 2013, Article ID 858139, 2 pages
http://dx.doi.org/10.1155/2013/858139
Case Report

Polyoma BK Virus: An Oncogenic Virus?

1Department of Internal Medicine, Henry Ford Hospital, 2799 West Boulevard, Detroit, MI 48202, USA
2Department of Medicine, Deccan College of Medical Sciences, Hyderabad 500058, India
3Department of Internal Medicine, Brookdale University Hospital and Medical Centre, Brooklyn, NY 11212, USA

Received 15 May 2013; Accepted 25 June 2013

Academic Editors: A. L. de Francisco, G. V. R. Prasad, and A. Shoker

Copyright © 2013 Syed Hassan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. B. Drachenberg, H. H. Hirsch, E. Ramos, and J. C. Papadimitriou, “Polyomavirus disease in renal transplantation: review of pathological findings and diagnostic methods,” Human Pathology, vol. 36, no. 12, pp. 1245–1255, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. T. P. Thamboo, K. J. M. Jeffery, P. J. Friend, G. D. H. Turner, and I. S. D. Roberts, “Urine cytology screening for polyoma virus infection following renal transplantation: the Oxford experience,” Journal of Clinical Pathology, vol. 60, no. 8, pp. 927–930, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. I. S. D. Roberts, D. Besarani, P. Mason, G. Turner, P. J. Friend, and R. Newton, “Polyoma virus infection and urothelial carcinoma of the bladder following renal transplantation,” British Journal of Cancer, vol. 99, no. 9, pp. 1383–1386, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. S. D. Gardner, A. M. Field, D. V. Coleman, and B. Hulme, “New human papovavirus (B.K.) isolated from urine after renal transplantation,” Lancet, vol. 1, no. 7712, pp. 1253–1257, 1971. View at Google Scholar · View at Scopus
  5. M. Tognon, A. Corallini, F. Martini, M. Negrini, and G. Barbanti-Brodano, “Oncogenic transformation by BK virus and association with human tumors,” Oncogene, vol. 22, no. 33, pp. 5192–5200, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Garcia-España, E. Salazar, T. T. Sun, X. R. Wu, and A. Pellicer, “Differential expression of cell cycle regulators in phenotypic variants of transgenically induced bladder tumors: implications for tumor behavior,” Cancer Research, vol. 65, no. 4, pp. 1150–1157, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. M. T. McCabe, J. A. Low, M. J. Imperiale, and M. L. Day, “Human polyomavirus BKV transcriptionally activates DNA methyltransferase 1 through the pRb/E2F pathway,” Oncogene, vol. 25, no. 19, pp. 2727–2735, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Das, K. Wojno, and M. J. Imperiale, “BK virus as a cofactor in the etiology of prostate cancer in its early stages,” Journal of Virology, vol. 82, no. 6, pp. 2705–2714, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. P. Monini, A. Rotola, L. de Lellis et al., “Latent BK virus infection and Kaposi's sarcoma pathogenesis,” International Journal of Cancer, vol. 66, no. 6, pp. 717–722, 1996. View at Google Scholar
  10. D. B. Weinreb, G. T. Desman, M. J. M. Amolat-Apiado, D. E. Burstein, J. H. Godbold Jr., and E. M. Johnson, “Polyoma virus infection is a prominent risk factor for bladder carcinoma in immunocompetent individuals,” Diagnostic Cytopathology, vol. 34, no. 3, pp. 201–203, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Negrini, P. Rimessi, C. Mantovani et al., “Characterization of BK virus variants rescued from human tumours and tumour cell lines,” Journal of General Virology, vol. 71, no. 11, pp. 2731–2736, 1990. View at Google Scholar · View at Scopus
  12. D. Geetha, B. C. Tong, L. Racusen, J. S. Markowitz, and W. H. Westra, “Bladder carcinoma in a transplant recipient: evidence to implicate the BK human polyomavirus as a causal transforming agent,” Transplantation, vol. 73, no. 12, pp. 1933–1936, 2002. View at Google Scholar · View at Scopus