Nephrotic Syndrome Secondary to Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits of Lambda Light Chain
Figure 4
Electron microscopic finding of kidney biopsy. Electron microscopy demonstrates diffuse podocyte foot process effacement, proliferation in the capillary loop, and remodeling of the glomerular basement membrane with cellular interposition (a). The glomerular basement membrane is markedly irregular in thickness, and dense deposits are located in the mesangial areas and focally within subendothelial space without any organized substructural features (b). In loops without these abnormalities, the glomerular basement membrane is of normal thickness and has normal architecture.
