Case Reports in Nephrology / 2014 / Article / Tab 1

Case Report

IgG4-Related Tubulointerstitial Nephritis Associated with Membranous Nephropathy in Two Patients: Remission after Administering a Combination of Steroid and Mizoribine

Table 1

Laboratory findings.

Case Case

Urinalysis; protein/blood3+/3+2+/2+
Urinary protein (g/day)1.42.73
Urinary 2MG (μg/L)11,080858 (ref, 0–230)
Urinary NAG (U/L)31.9151.2 (ref, 0–11.5)
Creatinine (mg/dL)1.0 0.9
CCr (mL/min)92.449.1
BUN (mg/dL)15.416.1
WBC (Eosinophil) (×109/L) (%)11.5 (47.5)7.4 (46.5)
Hemoglobin (g/dL)11.99.5
Hematocrit (%)35.428.5
Total protein (g/dL)9.37.6
Albumin (g/dL)2.21.7
AST (U/L)2743
ALT (U/L)1533
ALP (U/L)492480
Bilirubin, total (mg/dL)0.40.4
Amylase (U/L)60N/A
CRP (mg/dL)1.70.4
CH50 (U/mL)<5<5 (ref, 25–48)
C3 (mg/dL)3921 (ref, 86–160)
C4 (mg/dL)2.0 <2 (ref, 17–45)
Antinuclear antibody1 : 320 (Homo/Spec)<1 : 40
Anti-dsDNA antibodyNegativeNegative
Anti-Sm antibodyNegativeNegative
Anti-RNP antibodyNegative16.0
Anti-SSA antibodyNegativeNegative
Anti-SSB antibodyNegativeN/A
IgA (mg/dL)183386 (ref, 110–410)
IgM (mg/dL)37468 (ref, 83–190)
IgE (mg/dL)4131811 (ref, 0–202)
IgG (mg/dL)69896350 (ref, 870–1700)
IgG1 (mg/dL)17102460 (ref, 423–1080)
IgG2 (mg/dL)22801740 (ref, 265–931)
IgG3 (mg/dL)2491100 (ref, 5–121)
IgG4 (mg/dL)27501050 (ref, 4–108)
S-IL2 receptor (U/mL)39123973 (ref, 190–650)

Note: Conversion factors for units: Creatinine in mg/dL to μmol/L, ×88.4; CCr in mL/min to mL/s, ×0.01667; BUN in mg/dL to mmol/L, ×0.357; Hemoglobin, Total protein, and Albumin in g/dL to g/L, ×10; Bilirubin in mg/dL to mol/L, ×17.1; CRP in mg/dL to mg/L, ×10; IgA, IgM, IgE in mg/dL to mg/L, ×10; IgG, IgG1, IgG2, IgG3, and IgG4 in mg/dL to g/L, ×0.01. No conversion necessary for C3, C4 in mg/dL and g/L.
Abbreviations and definitions: 2MG, 2 microglobulin; NAG, N-acetyl-beta-D-glucosaminidase; CCr, creatinine clearance; WBC, white blood cell; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; CRP, C-reactive protein; ANCA, antineutrophil cytoplasmic antibody; IgA, immunoglobulin A; S-IL2 receptor, soluble interleukin-2 receptor; SPEP, serum protein electrophoresis; ref, reference range.