Hydralazine Induces Myeloperoxidase and Proteinase 3 Anti-Neutrophil Cytoplasmic Antibody Vasculitis and Leads to Pulmonary Renal Syndrome

Table 1

Hydralazine-induced ANCA vasculitis—patients with pulmonary renal syndrome, treatment, and outcome.

Article [reference]	Number of Patients	Positive MPO antibodies	Pulmonary and renal involvement	Treatment of patients with pulmonary renal syndrome	Outcome
Almroth et al. [13]	17	12 of 14 tested	4	C 4/4; Cy 2/4,; Az 1/4, P 1/4	3 out of 4 died
Short and Lockwood [14]	10	10	2	C 2/2; Cy 1/2	Not reported
Choi et al. [3]	10	10	5	C 5/5; Cy 5/5	1 out of 4 died
Yokogawa and Vivino [7]	2	2	1	C, Cy	Died
Marina et al. [11]	1	1	1	C, Cy	Died

C: corticosteroids; Cy: cyclophosphamide; Az: azathioprine; P: plasmapheresis.