Case Report
A Case of Concurrent MPO-/PR3-Negative ANCA-Associated Glomerulonephritis and Membranous Glomerulopathy
Table 1
Laboratory findings on admission.
| | Peripheral blood | | | WBC | 9800/μL | | Neutro | 78.1% | | RBC | 311 × 104/μL | | Hb | 10.2 g/dL | | Ht | 31.0% | | PLT | 26.3 × 104/μL | | Blood chemistry | | | AST | 17 IU/L | | ALT | 12 IU/L | | LDH | 286 IU/L | | ALP | 209 IU/L | | TP | 6.6 g/dL | | Alb | 2.7 g/dL | | BUN | 43 mg/dL | | Cr | 3.22 mg/dL | | Na | 144 mEq/L | | K | 4.3 mEq/L | | Cl | 111 mEq/L | | Ca | 8.0 mg/dL | | Pi | 4.0 mg/dL | | TC | 183 mg/dL | | LDL-C | 116 mg/dL | | TG | 121 mg/dL | | FPG | 83 mg/dL | | HbA1c | 5.5% | | Serology | | | CRP | 5.9 mg/dL | | IgG | 962 mg/dL | | IgA | 149 mg/dL | | IgM | 40 mg/dL | | C3 | 88 mg/dL | | C4 | 19 mg/dL | | CH50 | 30.5 U/mL | | TSH | 2.42 μIU/mL | | BNP | 1135.7 pg/mL | | KL-6 | 689 U/mL | | ANA | ×80 (speckled) | | dsDNAIgG | <5.0 IU/mL | | RA test | (−) | | MPO-ANCA | <10 E.U. | | PR3-ANCA | <10 E.U. | | Azurocidin-ANCA | (−) | | BPI-ANCA | (+) | | Cathepsin G-ANCA | (−) | | Elastase-ANCA | (+) | | Lactoferrin-ANCA | (−) | | Lysozyme-ANCA | (+) | | SS-A/RO | (−) | | SS-B/LA | (−) | | Anti-GBM | <10 E.U. | | Cryoglobulin | (−) | | HBs-Ag | (−) | | HCV-Ab | (−) | | TPHA | (−) | | Urine | | | U-protein | 5.13 g/day | | 24-hour-CCr | 21 mL/min | | Sediment | | | RBC | Many/HPF | | WBC | 50–99/HPF | | C-granule | 2+ | | C-RBC | 1+ |
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