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Case Reports in Nephrology
Volume 2016 (2016), Article ID 6713807, 5 pages
Case Report

Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review

1Division of Nephrology and Hypertension, Department of Internal Medicine, Wayne State University Detroit Medical Center, Detroit, MI, USA
2Department of Pathology, Wayne State University Detroit Medical Center, Detroit, MI, USA

Received 1 August 2016; Revised 5 October 2016; Accepted 3 November 2016

Academic Editor: Władysław Sułowicz

Copyright © 2016 Zeenat Yousuf Bhat et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Patients with advanced chronic kidney disease including ESRD patients may present with a wide spectrum of cutaneous abnormalities, ranging from xerosis to hyperpigmentation to severe deforming necrotizing lesions. Skin problems are not uncommon in this population of patients, with a clinical presentation that can be quite bizarre, mandating a long list of differential diagnostic possibilities, and subsequent rise of a puzzling diagnostic challenge. We describe an ESRD patient who presented with blistering, nonhealing ulcerative lesions with a diagnostic skin biopsy revealing a mixed pattern of linear IgA bullous dermatosis and dermatitis herpetiformis. A clinical remission could be achieved with pulse intravenous steroids followed by oral maintenance in combination with dapsone, with no evidence of recurrence.