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Case Reports in Nephrology
Volume 2018, Article ID 9787093, 6 pages
https://doi.org/10.1155/2018/9787093
Case Report

Posttransplant Lymphoproliferative Disorder Presenting as Testicular Lymphoma in a Kidney Transplant Recipient: A Case Report and Review of the Literature

1Montefiore Einstein Center for Transplantation, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA
2Department of Internal Medicine, Maimonides Medical Center, Brooklyn, NY, USA
3Albert Einstein College of Medicine, Bronx, NY, USA
4Department of Pathology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA

Correspondence should be addressed to Stuart Greenstein; gro.eroifetnom@tsneergs

Received 13 September 2017; Accepted 15 January 2018; Published 14 February 2018

Academic Editor: Władysław Sułowicz

Copyright © 2018 Steve Omoruyi Obanor et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Posttransplant lymphoproliferative disorder (PTLD) is a malignancy caused by the immunosuppression that occurs after transplantation. It is primarily a nodal lesion but frequently it involves extranodal masses. Treatment is usually by reducing immunosuppressive therapy. Testicular lymphoma as PTLD is notably rare in documented literature and there is limited evidence of definitive treatment guidelines. This manuscript describes a patient who developed diffuse large B-cell lymphoma of his right testis one year following kidney transplantation. A diagnosis of PTLD was made and treatment with rituximab, locoregional radiotherapy, and intrathecal methotrexate in addition to the standard reduction of immunosuppression resulted in complete remission until now. We submit this case along with literature review of similar cases in the past and a review of specific peculiarities of our case with emphasis on our treatment plan to further the understanding of this diversiform disease.