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Case Reports in Neurological Medicine
Volume 2013 (2013), Article ID 178291, 4 pages
Case Report

Isolated Bilateral Ptosis as an Early Sign of Guillain-Barré Syndrome

Department of Neurology (Medicine), Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar

Received 21 January 2013; Accepted 4 March 2013

Academic Editors: H. Ikeda, P. Sandroni, and M. Toft

Copyright © 2013 Yahia Z. Imam and Dirk Deleu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Guillain-Barré syndrome (GBS) has many variants with distinct presentations. Ptosis as an initial presentation is rare. Case Report. We describe a young female with bilateral ptosis without ophthalmoplegia as the initial presentation of Guillain-Barré ptosis in an anti-GQ1b IgG antibody negative patient with a favorable outcome to intravenous immunoglobulins. Objectives. Our paper highlights the importance of recognizing GBS as a potential etiology in a patient presenting with isolated ptosis, particularly since the course of GBS can be more dramatic than in the anti-GBQ1b syndromes such as ophthalmoparesis without ataxia and Miller Fisher syndrome or ocular myasthenia. Conclusion. This is the first paper of anti-GBQ1b antibody negative GBS presenting with isolated ptosis without ophthalmoparesis. GBS should be included in the list of differential diagnosis of such presentations.