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Case Reports in Neurological Medicine
Volume 2013, Article ID 356157, 4 pages
Case Report

An Unusual Case of Recurrent Guillain-Barre Syndrome of a Different Subtype Five Years after Initial Diagnosis

1Department of Pediatrics, University of California, San Diego and Rady Children’s Hospital, USA
2Departments of Neurosciences and Pediatrics, University of California, San Diego, Division of Child Neurology, Rady Children’s Hospital of San Diego, 8010 Frost Street, Suite 400, San Diego, CA 92123, USA

Received 16 March 2013; Accepted 2 April 2013

Academic Editors: P. Berlit, S. T. Gontkovsky, H. Ikeda, R. Koide, and Y. Wakabayashi

Copyright © 2013 M. Dy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We present a case of a previously healthy 17-year-old girl with history of Guillain-Barre Syndrome 5 years after initial presentation who presented with bilateral lower extremity pain, worsening dysphagia, subsequent weakness, and decreased reflexes. Cerebrospinal fluid analysis had a prominent lymphocytic pleocytosis. MRI of spine showed significant anterior nerve root enhancement. Electromyogram demonstrated a mild axonal greater than demyelinating motor polyneuropathy and intact sensory responses, with no evidence of conduction block or temporal dispersion, unlike her first presentation that revealed a demyelinating polyneuropathy. The patient recovered with mild subjective weakness following 5 days of intravenous immunoglobulin treatment. This case represents a recurrence of a predominantly motor variant polyradiculoneuropathy distinct from the initial presentation with a lymphocytic predominant CSF pleocytosis, nerve root enhancement on MRI spine, and rapid recovery following treatment with intravenous immunoglobulin.