Ovarectomy despite Negative Imaging in Anti-NMDA Receptor Encephalitis: Effective Even Late
Figure 1
Axial FLAIR magnetic resonance (MR) imaging (A) shows bilateral hyperintense signal in the mildly swollen medial temporal lobe (arrows). Histological examination (B and C) of the resected ovar revealed a cystic teratoma of 2.9 cm diameter including focal neuronal differentiation of ~0.5 cm diameter. Immunohistochemistry of glial fibrillary acidic protein (B; magnification 25) and neuron specific enolase (C; magnification 400) underlined the presence of focal glial and partial neuronal differentiation. Other parts of the teratoma showed squamous epithelial differentiation with hair follicles, sweat as well as sebaceous glands and fat/connective tissue, respiratory epithelia, cartilage as well as osteocytes with bone matrix, and also haematopoiesis.
