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Case Reports in Neurological Medicine
Volume 2013, Article ID 940438, 4 pages
Case Report

Primary Angiitis of the Central Nervous System: A Report of Three Cases from a Single Colombian Center

1Internal Medicine Unit, Fundación Valle del Lili, CES University, Cali, Colombia
2Rheumatology Unit, Fundación Valle del Lili, ICESI University, Colombia
3Clinical Neurology Unit, Fundación Valle del Lili, Cali, Colombia
4Pathology Unit, Fundación Valle del Lili, Cali, Colombia

Received 17 March 2013; Accepted 14 April 2013

Academic Editors: P. Berlit, S. T. Gontkovsky, R. Koide, V. Rajajee, and Y. Wakabayashi

Copyright © 2013 Nicolás Coronel-Restrepo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The primary angiitis of the central nervous system (PACNS) is an entity with a very low incidence and prevalence. It is not clear why the inflammatory process of this entity is limited to the cerebral vasculature without systemic manifestations. Its clinical manifestations are very heterogeneous and make clinical diagnosis difficult. In most cases, a brain biopsy is required. Only the clinical suspicion and the ability to recognize the possible clinical and imagenological patterns of presentation make an accurate diagnosis possible. The vast majority of the treatment recommendations are given by series of case reports. The following paper described the clinical, imagenological, and histopathological characteristics of three Colombian patients with PACNS. The strategic therapeutic used in shown.