Case Reports in Neurological Medicine / 2014 / Article / Tab 2

Case Report

Osmotic Demyelination Syndrome as the Initial Manifestation of a Hyperosmolar Hyperglycemic State

Table 2

Reported cases of CMP associated with HHS.

Author*Age yr.GenderGluOsmKetonesNaNaçMRITASAOutcome

McComb et al. [16]54F954NSNegative169188NoNMDied
O’Malley et al. [17]49F1910399Trace134166Yes9 daysACFR
Burns et al. [18]93M524343Negative137140Yes2 daysACFR
Mao et al. [19]55M685318Negative134NSYes0 days+NED
Guerrero et al. [20]25M>700NSNSNSNSYesNSNS
This report47M838320Negative133138Yes0 daysNED

+Patient had history of multiple focal seizures 3 weeks before admission.
CPM, central pontine myelinolysis; HHS, hyperosmolar hyperglycemic state; Glu, glucose on admission; Osm, osmolality; Na, sodium at admission; Naç, maximum sodium; MRI, magnetic resonance imaging; TASA, time after admission of symptoms; NM, not mentioned; ACFR, almost complete functional recovery; NED, no evidence of disease.
Glu (mg/dL); Osm (mOsm/kg); Na (mEg/L).

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