Cerebellum as Initial Site of Distant Metastasis from Papillary Carcinoma of Thyroid: Review of Three Cases

Table 1

Reported cases of cerebellar metastasis from papillary thyroid carcinoma.

Reference	Age (years)/sex	Symptoms	Location	Treatment	Status	Follow-up
Tanaka et al. [1]	65/F	Lateral gazing nystagmus and slurred speech	Left cerebellar hemisphere with intratumoral hemorrhage	Subtotal resection; Gamma knife surgery 15 Gy	Alive and disease-free	23 months
Cha et al. [2]	78/F	—	Left cerebellar hemisphere	Subtotal resection; Gamma knife surgery 15 Gy	Alive and disease-free	36 months
Aguiar et al. [3]	33/F	Raised ICP	Right cerebellar hemisphere + cerebral lesions	Subtotal resection; Radiation 40 Gy/20 fractions	At 12 months, developed frontal lobe metastasis; Treated with surgery; At 36 months, alive and disease-free	36 months
Lecumberri et al. [4]	65/F	—	—	Surgery and radiotherapy	At 48 months, developed cerebellar recurrence with intratumoral hemorrhage; Treated with surgery	84 months
Pazaitou-Panayiotou et al. [5]	69/M	Dizziness, headaches, and ataxia	Right cerebellar hemisphere	Subtotal resection and RT 39 Gy/13 fractions	Dead with disease	4 months
Al-Dhahri et al. [6]	75/F	Dizziness, headache, and vomiting		Complete resection and RAI	—	—
Carcangiu et al. [7]	50/F	—	Right cerebellar hemisphere	Complete resection and RAI	Alive and disease-free	96 months
Honma et al. [8]	60/M	Incidental	Right cerebellar hemisphere	Surgery	Alive and disease-free	24 months
Xu et al. [9]	—	Incidental	Right cerebellar hemisphere	Surgery	—	—
Lin et al. [10]	Two cases	Headaches, ataxia, and vomiting	Case 1: bilateral cerebellar hemispheres with obstructive hydrocephalus; Case 2: left cerebellar hemisphere	Complete resection	—	—
Jyothirmayi et al. [11]	—	Headache, ataxia	Left cerebellar hemisphere	Complete resection	—	—
Pacak et al. [12]	—	—	—	Complete resection	—	—