Advanced Genetic Testing Comes to the Pain Clinic to Make a Diagnosis of Paroxysmal Extreme Pain Disorder

Table 3

SCN9A-associated features questionnaire. The responses of the patient described in this case report are shown.

Have you ever had (including early childhood):	Yes/no	If yes, at what age did those features begin?	If yes, how often (sometimes, often, always)
Seizures	No
Rectal pain	Yes	45-increased in severity	often
Constipation	Yes	3	always
Sensitivity to cold temperatures	Yes	51	always (likes ambient temperature of 27°C)
Redness and swelling of the hands or feet	Yes	36 (during pregnancy)
Pain during/following tear secretion	No (pain when eyes dry)
Pain during/following flushing	No
Pain during/following sinus congestion	Yes	37	sometimes
Pain during/following defecation	Yes	45	always
Pain during/following eating	No
Pain during/following strong emotions	Yes	53	often