Sellar Metastasis of Cervical Adenocarcinoma

Figure 3

(a) Frozen section tissue showing interface between mucinous adenocarcinoma metastasis and adjacent adenohypophysis (arrow), H&E, 40x. (b) Metastatic mucinous adenocarcinoma showing clusters of moderately pleomorphic epithelial cells floating in pools of mucin separated by fibrovascular septae of variable thickness, H&E, 200x. (c) Cytokeratin CK8/18 is positive in tumor cells; immunohistochemical stain, 200x. (d) p16 shows nuclear positivity; immunohistochemical stain, 200x.

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