Stiff-Person Syndrome: Seeing Past Comorbidities to Reach the Correct Diagnosis

Table 1

Diagnostic criteria of stiff-person syndrome [7].

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Diagnostic criteria of stiff-person syndrome

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(i) Stiffness in the axial and limb muscles resulting in impairment of ambulation

(ii) Presence of superimposed episodic spasms that are precipitated by sudden movement, noise, or emotional upset

(iii) A positive therapeutic response to oral diazepam or findings of continuous motor-unit activity on electromyography (EMG) that are abolished by intravenous diazepam

(iv) Absence of other neurologic disorders that may explain the clinical features

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