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Case Reports in Obstetrics and Gynecology
Volume 2012 (2012), Article ID 862472, 5 pages
Case Report

Epithelioid Trophoblastic Tumor: A Case Report and Review of the Literature

1Department of Gynecologic Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA
2Department of Pathology, Breast, and Gynecologic Pathology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA

Received 16 September 2012; Accepted 10 November 2012

Academic Editors: I. Hoesli, I. Kowalcek, S. Salhan, K. Takeuchi, and E. Vaisbuch

Copyright © 2012 Eirwen M. Scott et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Epithelioid trophoblastic tumor (ETT) is a rare gestational trophoblastic tumor. Cases of ETT present as abnormal vaginal bleeding in women of reproductive age, with low human chorionic gonadotropin (hCG) levels. ETT can be a sequela of any gestational event and can present in both intrauterine and extrauterine sites. Metastasis and death have been reported. We present a case of a 44-year-old female incidentally diagnosed with ETT following laparoscopic-assisted vaginal hysterectomy. Postoperative evaluation for metastatic disease was negative. The patient has been closely followed and remains disease free 8 months postoperatively. ETT presents a diagnostic challenge due to its rarity and histologic resemblance to other pathologies. ETT is relatively chemoresistant and managed surgically. Misdiagnosis delays effective treatment and affects survival.