Pregnancy with a Severe Hemoglobinopathy: Unintended Consequences of Transfusions

Table 1

Important lab values from admission to hospital to 2 follow-up outpatient visits.

	Admission	Day 0	Day 1		Day 2		Day 3		Day 4	Day 5	Day 6	Day 7	Day 8	Outpatient-PD day 2	Outpatient-PD 3 weeks
Hb (g/dL)	8.3	6.0	7.7	7.0	5.8	8.2	6.5	6.4	5.7	5.3	5.4	5.2	5.1	5.4	6.8
Hematocrit (%)	26.1	19.0	23.6	21.2	18.2	24.8	19.9	19.4	17.4	16.0	16.9	16.7	16.6	18.0	23.3
WBC (K/μL)	13.6	—	7.9	—	6.6	—	—	—	4.5	5.3	6.6	8.5	10.3	11.0	7.9
RBC (K/μL)	3.85	—	3.29	—	3.38	—	—	—	2.53	2.39	2.39	2.61	2.59	2.78	3.56
Platelet (K/μL)	222	—	159	—	154	—	—	—	168	171	157	236	198	250	249
MCV (fL)	68	—	71.6	—	73.4	—	—	—	68.9	66.9	66.1	64	64	64.6	65.5
RDW (%)	33.9	—	34.1	—	33.2	—	—	—	38.7	33.9	32.6	31.5	31.1	32.1	30.8
Retic count (%)	—	—	—	—	3.5	—	3.4	—	3.3	4.8	3.8	5.2	6.1	6.4	—
BUN (mg/dL)	16	—	14	—	11	—	—	—	—	—	—	—	—	—	—
Creatinine (mg/dL)	0.53	—	0.48	—	0.45	—	0.40	—	0.42	0.46	0.46	0.50	0.51	0.49	—
LDH (U/L)	635	—	624	—	803	—	763	—	809	904	865	838	829	470	—
Total bilirubin (mg/dL)	10.0	—	6.3	—	9.9	—	11.1	—	10.6	14.0	10.7	8.0	6.7	3.9	2.2
Direct bilirubin (mg/dL)	—	—	2.1	—	5.1	—	—	—	7.6	10.1	7.6	5.6	4.7	2.6	1.2
AST (U/L)	—	—	—	—	30	—	—	—	25	—	—	—	—	—	—
ALT (U/L)	—	—	—	—	9	—	—	—	9	—	—	—	—	—	—
Alk phos (U/L)	—	—	—	—	131	—	—	—	165	—	—	—	—	—	—
Temperature (°C)	38.2	36.1	38.1	36.8	36.8	39.3	37.2	37.0	37.0	37.1	36.8	36.7	36.6	37.1	—
Heart rate (bpm)	139	111	85	123	130	92	116	124	101	109	110	118	107	68	78
Respiratory rate (breaths/min)	16	23	20	30	39	9	16	20	18	20	18	16	20	15	—
Transfusions completed (packed RBCs)	—	2 units	—	—	2 units	—	—	—	—	—	—	—	—	—	—