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Case Reports in Obstetrics and Gynecology
Volume 2013, Article ID 835316, 3 pages
Case Report

Vaginal Atrophy following Long-Term Depot Medroxyprogesterone Acetate Use: A Case Report

Department of Obstetrics and Gynecology, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA

Received 7 January 2013; Accepted 28 January 2013

Academic Editors: E. Cosmi, C. S. Hsu, T. Levy, and E. Shalev

Copyright © 2013 Christie Walker and Shawky Z. A. Badawy. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Depot medroxyprogesterone acetate (DMPA) is a commonly used form of contraception, with noncontraceptive benefits for the user. The mode of action is through the suppression of ovulation. It leads to hypoestrogenism which causes dryness of the vagina and dyspareunia. We present in this paper a patient that was very symptomatic with regard to vaginal atrophic changes determined by vaginal cytology. This side effect may become increasingly more common as we see more long-term use of DMPA.