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Case Reports in Obstetrics and Gynecology
Volume 2014, Article ID 582890, 3 pages
Case Report

HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy

Department of Gynecology and Obstetrics, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey

Received 3 June 2014; Accepted 4 September 2014; Published 17 September 2014

Academic Editor: Kyousuke Takeuchi

Copyright © 2014 Zeynep Ozcan Dag et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Preeclampsia is a leading cause of maternal mortality and morbidity worldwide. The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality for women and their infants alike. Hormonal changes during pregnancy and the puerperium carry an increased risk of venous thromboembolism including cerebral venous sinus thrombosis (CVST). Factor 5 leiden (FVL) is a procoagulant mutation associated primarily with venous thrombosis and pregnancy complications. We report a patient with FVL mutation who presented with CVST at 24th week of pregnancy and was diagnosed as HELLP syndrome at 34th week of pregnancy.