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Case Reports in Obstetrics and Gynecology
Volume 2014, Article ID 603097, 5 pages
Case Report

Obstructive Small Bowel Metastasis from Uterine Leiomyosarcoma: A Case Report

1Radiation Oncology, King Fahad Medical City, Riyadh, Saudi Arabia
2Radiation Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh 59046, Saudi Arabia
3Medical Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh 59046, Saudi Arabia
4Radiation Oncology, King Fahad Medical City, Riyadh 59046, Saudi Arabia
5Anatomic Pathology, King Fahad Medical City, Riyadh 11525, Saudi Arabia
6Clinical Oncology, Minia Oncology Center, Minia, Egypt

Received 4 December 2013; Accepted 15 January 2014; Published 4 March 2014

Academic Editors: C. S. Hsu and C.-C. Liang

Copyright © 2014 Mutahir A. Tunio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Uterine leiomyosarcoma is a rare and aggressive gynecologic malignancy with an overall poor prognosis. Lungs, bones, and brain are common sites of metastases of uterine leiomyosarcoma. Metastases of uterine leiomyosarcoma to the small bowel are extremely rare, and only four case reports have been published to date. Case presentation. A 55-year-old Saudi woman diagnosed with a case of uterine leiomyosarcoma treated with total abdominal hysterectomy (TAH) and bilateral salpingooophorectomy (BSO) presented in emergency room after sixteen months with acute abdomen. Subsequent work-up showed a jejunal mass for which resection and end-to-end anastomosis were performed. Biopsy confirmed the diagnosis of small bowel metastasis from uterine leiomyosarcoma. Further staging work-up showed wide spread metastasis in lungs and brain. After palliative cranial irradiation, systemic chemotherapy based on single agent doxorubicin was started. Conclusion. Metastatic leiomyosarcoma of small bowel from uterine leiomyosarcoma is a rare entity and is sign of advanced disease. It should be differentiated from primary leiomyosarcoma of small bowel as both are treated with different systemic chemotherapeutic agents.