Case Report
An Unusual Case of Fulminant Type 1 Diabetes during the Second Trimester of Pregnancy
Table 1
Laboratory findings upon admission.
| | Urinalysis | Ketone body 3+, glucose 4+ |
| | Arterial blood gas analysis | pH 6.98, PaO2: 129.0 mmHg, and
PaCO2: 9.3 mmHg |
| | 1 mmol/L, base excess −27.6 mmol/L |
| | Complete blood count | WBC: 32,050/L; hemoglobin: 13.6 g/dL; hematocrit: 41.5%; platelets: 37.9 × 104/L; glucose: 950 mg/dL; HbA1c: 5.7% |
| | Biochemistry | TP: 8.4 g/dL; albumin: 4.5 g/dL;
GOT: 32 IU/L; GP: 23 IU/dL;
LDH: 478 IU/L; gamma-GTP: 13 IU/L; amylase: 709 IU/L; CRP: 5.03 mg/dL;
BUN: 37 mg/dL; creatinine: 1.58 mg/dL;
Na: 128 mEq/L; K: 5.5 mEq/L; and Cl: 88 mEq/L |
| | Coagulation | PT: 22.8 seconds;
APTT: 42.4 seconds;
INR: 1.20 seconds;
Fibrinogen: 457 mg/dL;
D-dimers: 106.3 g/mL |
| | Antibodies | Insulin antibodies <125.0 nU/mL;
GAD antibodies <1.3 U/mL;
IA-2 antibodies <0.4 U/mL;
C-peptide 0.1 ng/mL (2 h after meal) |
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Note: WBC: white blood cells; CRP: C-reactive protein; TP: total protein; GOT: glutamate-oxaloacetate transaminase; GPT: glutamate pyruvate transaminase; LDH: lactic dehydrogenase; gamma-GTP: gamma-glutamyl transpeptidase; BUN: blood urea nitrogen; PT: prothrombin time; APTT: activated partial thromboplastin time; INR: international normalized ratio; PaO2: partial oxygen pressure; PaCO2: partial carbon dioxide pressure; GAD: glutamic acid decarboxylase; IA-2: islet antigen-2.
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