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Case Reports in Obstetrics and Gynecology
Volume 2015, Article ID 171828, 3 pages
Case Report

Primary Hyperparathyroidism in Pregnancy: A Two-Case Report and Literature Review

Department of Endocrinology and Nutrition, Reina Sofia University Hospital, Avenida Menéndez Pidal, s/n, 14004 Córdoba, Spain

Received 31 January 2015; Accepted 15 March 2015

Academic Editor: Svein Rasmussen

Copyright © 2015 A. D. Herrera-Martínez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary hyperparathyroidism (PHPT) in pregnant women is an uncommon disease. It could be easily misdiagnosed because of physiologic changes during pregnancy; in some cases, patients could remain asymptomatic maintaining elevated calcium serum levels, and this situation represents a threat to the health of both mother and fetus. We present two cases of PHPT during pregnancy and their evolution after surgical treatment in the second trimester; there were no observed complications during pregnancy or delivery in our patients. Early diagnosis and medical/surgical treatment in PHPT are necessary for avoiding maternal and fetal complications which could not be predicted based on duration or severity of hypercalcemia. An appropriate management of PHPT during pregnancy is necessary for preserving the health of both the woman and the fetus.