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Case Reports in Obstetrics and Gynecology
Volume 2015, Article ID 276931, 4 pages
Case Report

Successful Pregnancy in a Couple with Severe Male Factor Infertility after Selection of Sperm with Cytoplasmic Droplets

1Department of Obstetrics and Gynecology, Rutgers-New Jersey Medical School, 185 South Orange Avenue, MSB-E506, Newark, NJ 07103, USA
2University Reproductive Associates, 214 Terrace Avenue, Hasbrouck Heights, NJ 07604, USA
3New York University Langone Medical Center, NYU Fertility Center, 660 1st Avenue, New York, NY 10016, USA
4Department of Obstetrics and Gynecology, Texas Tech University School of Medicine, Lubbock, TX 79430, USA
5Department of Obstetrics and Gynecology, Mount Sinai St. Luke’s Roosevelt Hospital, 1000 Tenth Avenue, Suite 10C, New York, NY 10019, USA

Received 7 May 2015; Accepted 7 July 2015

Academic Editor: Erich Cosmi

Copyright © 2015 Jenna Bellish et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We present live births resulting from two separate IVF cycles in a couple in which ICSI was performed with sperm specifically selected for presence of small cytoplasmic droplets. These cycles followed previous cycles using standard sperm selection methods in which very poor embryo development and no pregnancies ensued. The male partner was diagnosed with severe male factor infertility including elevated DNA fragmentation.