Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Obstetrics and Gynecology
Volume 2017, Article ID 8357235, 4 pages
https://doi.org/10.1155/2017/8357235
Case Report

Bilateral Sertoli Cell Tumors in a Patient with Androgen Insensitivity Syndrome

1Department of Obstetrics and Gynecology, Santa Casa de Misericórdia, Vitória, ES, Brazil
2Santa Casa de Misericórdia, Vitória, ES, Brazil

Correspondence should be addressed to Roberta Fonseca de Souza; moc.liamg@2070acesnofatrebor

Received 19 September 2016; Accepted 27 February 2017; Published 13 March 2017

Academic Editor: Hans Rudolf Tinneberg

Copyright © 2017 Roberta Fonseca de Souza et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. M. Morris, “The syndrome of testicular feminization in male pseudohermaphrodites,” American Journal of Obstetrics and Gynecology, vol. 65, no. 6, pp. 1192–1211, 1953. View at Publisher · View at Google Scholar · View at Scopus
  2. A. L. M. Boehmer, H. Brüggenwirth, C. van Assendelft et al., “Genotype versus phenotype in families with androgen insensitivity syndrome,” The Journal of Clinical Endocrinology & Metabolism, vol. 86, no. 9, pp. 4151–4160, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. I. A. Hughes, J. D. Davies, T. I. Bunch, V. Pasterski, K. Mastroyannopoulou, and J. MacDougall, “Androgen insensitivity syndrome,” The Lancet, vol. 380, no. 9851, pp. 1419–1428, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. E. G. Perez and G. Guerra Jr., “Hormônio anti-mülleriano: revisão e contribuição para a investigação das ambigüidades genitais,” Arquivos Brasileiros de Endocrinologia & Metabologia, vol. 44, no. 5, pp. 425–433, 2000. View at Publisher · View at Google Scholar
  5. M. A. Fritz and L. Speroff, Clinical Gynecologic Endocrinology and Infertility, Lippincott Williams & Wilkins, Philadelphia, Pa, USA, 8th edition, 2011.
  6. S. Khan and L. B. Craig, “A review of radiologic imaging in patients with androgen insensitivity,” Journal of Genital System & Disorders, vol. 1, 2013. View at Publisher · View at Google Scholar
  7. N. Jorgensen, J. Muller, A. Giwercman, and N. E. Skakkebaek, “Clinical and biological significance of carcinoma in situ of the testis,” Cancer Surveys, vol. 9, no. 2, pp. 287–302, 1990. View at Google Scholar · View at Scopus
  8. M. S. Verp and J. L. Simpson, “Abnormal sexual differentiation and neoplasia,” Cancer Genetics and Cytogenetics, vol. 25, no. 2, pp. 191–218, 1987. View at Publisher · View at Google Scholar · View at Scopus
  9. R. Deans, S. M. Creighton, L.-M. Liao, and G. S. Conway, “Timing of gonadectomy in adult women with complete androgen insensitivity syndrome (CAIS): patient preferences and clinical evidence,” Clinical Endocrinology, vol. 76, no. 6, pp. 894–898, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Manuel, K. P. Katayama, and H. W. Jones Jr., “The age of occurrence of gonadal tumors in intersex patients with a Y chromosome,” American Journal of Obstetrics and Gynecology, vol. 124, no. 3, pp. 293–300, 1976. View at Publisher · View at Google Scholar · View at Scopus
  11. N. Howlader, A. M. Noone, M. Krapcho et al., Eds., SEER Cancer Statistics Review, 1975–2013, National Cancer Institute, Bethesda, Md, USA, 2016.
  12. A. Hashmi, F. Hanif, S. M. Hanif, F. E. Abdullah, and M. S. Shamim, “Complete androgen insensitivity syndrome,” Journal of the College of Physicians and Surgeons Pakistan, vol. 18, no. 7, pp. 442–444, 2008. View at Google Scholar · View at Scopus
  13. D. L. S. Danilovic, P. H. S. Correa, E. M. F. Costa, K. F. S. Melo, B. B. Mendonca, and I. J. P. Arnhold, “Height and bone mineral density in androgen insensitivity syndrome with mutations in the androgen receptor gene,” Osteoporosis International, vol. 18, no. 3, pp. 369–374, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. D. Kravarusic, E. Seguier-Lipszyc, E. Feigin, R. Nimri, N. Nagelberg, and E. Freud, “Androgen insensitivity syndrome: risk of malignancy and timing of surgery in a paediatric and adolescent population,” African Journal of Paediatric Surgery, vol. 8, no. 2, pp. 194–198, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. I. E. Gürer, A. E. Demirkiran, and M. Sare, “Sertoli cell tumor in two sibs with testicular feminization syndrome,” Turkish Journal of Medical Sciences, vol. 30, pp. 385–387, 2000. View at Google Scholar
  16. I. Gómez García, M. Romero Molina, A. López-García Moreno et al., “Sertoli cell tumor, a rare testicular tumor, our experience and review of the literature,” Archivos Españoles de Urología, vol. 63, no. 5, pp. 392–395, 2010. View at Google Scholar · View at Scopus
  17. R. Pérez-Becerra, Z. Santana-Ríos, S. Fulda-Graue et al., “Sertoli-Leydig cell gonadal stroma tumors in the Dr. Manuel Gea González General Hospital,” Revista Mexicana de Urología, vol. 69, pp. 174–177, 2009. View at Google Scholar
  18. J. H. Davies, E. J. Knight, A. Savage, J. Brown, and P. S. Malone, “Evaluation of terminology used to describe disorders of sex development,” Journal of Pediatric Urology, vol. 7, no. 4, pp. 412–415, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. L. M. Liao, “Learning to assist women born with atypical genitalia: journey through ignorance, taboo and dilemma,” Journal of Reproductive and Infant Psychology, vol. 21, no. 3, pp. 229–238, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. R. Illig, C. DeCampo, M. R. Lang-Muritano et al., “A physiological mode of puberty induction in hypogonadal girls by low dose transdermal 17β-oestradiol,” European Journal of Pediatrics, vol. 150, no. 2, pp. 86–91, 1990. View at Publisher · View at Google Scholar · View at Scopus
  21. V. Sobel, B. Schwartz, Y.-S. Zhu, J. J. Cordero, and J. Imperato-McGinley, “Bone mineral density in the complete androgen insensitivity and 5α-reductase-2 deficiency syndromes,” Journal of Clinical Endocrinology and Metabolism, vol. 91, no. 8, pp. 3017–3023, 2006. View at Publisher · View at Google Scholar · View at Scopus