Case Report

Elevated CA 125 in a CASE of Leaking Endometrioma

Table 1

Summary of cases of ruptured endometrioma with elevated CA 125 levels†.

Author & YearType of study and number of patients (n)CA-125 level (IU/ml)Clinical presentationImaging findingsOperative intervention / Management

Johansson J et al. (1998) [5]Case report n = 19300Abdominal painUSS: Rt homogeneous ovarian 7x10cmLaparotomy, Excision of endometrioma

Kashyap RJ. (1999) [6]Case report n = 16114
Abdominal pain, NauseaUSS: 11 cm complex cystLaparotomy, Rt oophorectomy

Kurata, H et al. (2002) [7]Case report n = 19537Abdominal painUSS: homogenous bilateral ovarian cysts, FF in pelvis
MRI: ovarian masses, bloody liquid with T1- high signal and T2-low signal
Laparoscopy, enucelation of cysts

Cengiz et al. (2012) [8]Case report n = 1174.87Abdominal pain, NauseaUSS: Lt heterogenous adnexal mass 6x8cm, FF in pelvisLaparoscopy, Enucleation of cyst

A.K. Rani et al. (2012) [9]Case report n = 19391Abdominal painUSS: Rt homogenous adnexal mass 10.5x7cm, moderate ascites
CT: b/l adnexal mass, minimal ascites, nil lymphadenopathy
Laparotomy, excision of endometrioma

Duran M et al. (2013) [10]Case report n = 12556Pelvic and Abdominal pain, DysuriaUSS & CT: Lt heterogenous adnexal mass 5x5cmLaparoscopy, Excision of endometrioma

Dereli et al. (2014) [11]Case report n = 1143.72Bilateral pelvic massesUSS: hypoechoic bilateral adnexal massesLaparoscopy, Rt adnexectomy, Lt cystectomy

X. Dai et al. (2015) [12]Retrospective cohort
n = 43
797.89 ± 1106.52Abdominal pain, Pelvic mass, Asymptomatic-Laparoscopy/ Laparotomy

USS: ultrasound; CT: computerised tomography; MRI: magnetic resonance imaging; FF: free fluid; PoD: pouch of Douglas.
†In all cases reviewed endometrioma was confirmed histologically.