Abruptio Placentae Caused by Hypertriglyceridemia-Induced Acute Pancreatitis during Pregnancy: Case Report and Literature Review

Table 1

Case literatures of acute pancreatitis induced by hypertriglyceridemia during pregnancy.

First Author	Year	Age	G/P	Birth	Medication	Other	Mode BW	Indication	Laboratory	After Treatment
Billion JM [3]	1991	32		35	TPN
Achard JM [4]	1991				Two; Lipaphereses
Perrone G [5]	1996	37		35	Diet,; Gemfibrozil
İbrahim Bildirici [6]	2002	26	G2P2	24	Insulin,; Plasmapheresis		C/S	Fetal Distress (750 g)	Serum Amylase: 487; Panc. Amylase: 184; Panc Lipase:786; TG: 2316
Chee-Chuen Loo [7]	2002	37	G3P2	37	Ranitidine,; Heparin,; Insulin		SVD		Serum Amylase: 956 TG: 2066	Serum Amylase: 39 TG: 492
J.C. Sleth [8]	2004	28	G2P1	37	Heparin		C/S	Unstable Condition of the Mother	TG: 2316; Cholesterol: 1000; Panc. Amylase: 574; Panc. Lipase: 1310	TG: 100
A. Abu Musa [9]	2006	39	G2P1	28	Plasmapheresis		C/S	A Repeat C/S Delivery	TG: 3810; Panc. Amylase: 525; Panc. Lipase: 3524	TG: 591; Panc. Amylase: 79; Panc. Lipase: 396
Shih-Chang Chuang [10]	2006	28	G1P0	34	Antibiotics,; TPN	Pancreatic Necrosectomy,; Right Hemicolectomy; Ileostomy,; Cholecystostomy,; Gastrostomy,; Feeding Jejunostomy		Unstable Condition of the Mother	TG: 2184; Panc. Amylase: 1365; Panc. Lipase: 533	TG: 319
Alptekin Gürsoy [11]	2006	24	G1P0	37			C/S; (3230 g)	Fetal Distress	TG: 10092; Cholesterol: 1159; Panc. Amylase: 367; Panc. Lipase: 797	TG: 143; Cholesterol: 274; Panc Amylase: 23; Panc Lipase: 41
V. Exbrayat [12]	2007	31		33	Plasmapheresis, Heparin		C/S	Fetal Distress	TG: 11300; Cholesterol: 2500; Panc Amylase: 334; Panc Lipase: 168	TG: 1000
Luminita S. Crisan [13] - 1	2008	27	G2P0	35	TPN, Analgesics, Bowel Rest	ARDS	C/S; (2653 g)	Fetal Distress
Luminita S. Crisan [13] - 2	2008	29	G3P1	30	TPN, Analgesics, Bowel Rest	Acute Myocardial Infarction	Forceps–; Assisted; Vaginal; Delivery; (1854 g)
Luminita S. Crisan [13] - 3	2008	34	G3P0	33	TPN, Analgesics, Bowel Rest	ARDS	SVD; (2147 g)
Luminita S. Crisan [13] - 4	2008	23	G1P0	35	TPN, Analgesics, Bowel Rest		C/S (2498 g)	Low BPP
L. Vandenbroucke [14]	2009	34		37	Heparin,; A Low-Fat Diet		C/S (3940 g)	Fetal Distress	TG: 8447	TG: 240
Dilek Altun [15] - 1	2012	27	G1P0	5	Plasmapheresis, Heparin			Termination	TG: 2225; Cholesterol: 470; Panc. Amylase: 959	TG: 278; Cholesterol: 181
Dilek Altun [15] - 2	2012	24	G1P0	34	Plasmapheresis, A Low-Fat Diet		C/S (3100 g)		TG: 2699; Cholesterol: 230; Panc. Amylase: 956; Panc. Lipase: 2580	TG: 570; Cholesterol: 2500; Panc. Amylase: 208; Panc. Lipase: 208
Mindaugas Serpytis [16]	2012	31	G2P0	33	Heparin, Insulin, Plasmapheresis				TG: 1576	TG:183
Kumar Thulasidass [17] - 1	2013	37	G3P0	14	Insulin,; Metformin,; Fish Oil Therapy	Termination			TG: 1421; Cholesterol: 481; Serum Amylase: 1464	TG: 111; Cholesterol:93
Kumar Thulasidass [17] - 2	2013	24	G1P0	8		ARDS	Spontaneous Abortion		TG: 839; Cholesterol: 300; Serum Amylase: 8962	TG: 57; Cholesterol:77
Rafet Basar [18] - 1	2013	32	G3P0	37	Heparin,; Fatty Acids, DF		C/S	Elective	TG: 1400	TG: 380
Rafet Basar [18] - 2		30	G2P1	36	Heparin,; Fatty Acids,; DF, Plasmapheresis		C/S	Elective	TG: 12000	TG: 758
Ying Hang [19]	2013	31	G2P0	27		Noninvasive Positive; Pressure Ventilation; (NPPV), Drainage of; Chylous Ascites,; Peritoneal Lavage, ARDS	C/S; (1180 g)	Fetal Distress	TG: 523; Cholesterol:325; Panc. Amylase: 178	TG: Normal; Cholesterol: Normal
Bahiyah Abdullah [20]	2014	25	G4P3	8		Diagnostic Laparoscopy,; Acute Hemorrhagic Pancreatitis	Spontaneous Abortion		Serum Amylase: 1273	Serum Amylase: 147
Tejal Amin [21]	2014	40	G5P4	18	Insulin	IUMF			TG: 836; Cholesterol: 300	TG: 90
Natasha Gupta [22]	2014	32	G5P4	38	Plasmapheresis	Preeclampsia,; Pleural Effusion,; Chronic Pericarditis,; Retinal Detachment	C/S	Unstable Condition of the Mother	TG: 12.570; Cholesterol: 1067; Panc. Amylase: 1617; Panc. Lipase: 1330	TG: 295; Cholesterol: 179
Fadi Safi [23]	2014	24	G9P8	35	Plasmapheresis		C/S; (1720 gr)	Unresponsiveness to Treatment	TG: 2661; Cholesterol: 683; Serum Amylase: 802	TG: 425
Rachel Lim [24]	2015	27	G1P0	33	Insulin,; Plasmapheresis	Placental Abruption	SVD		TG: 720; Cholesterol: 90; Panc. Lipase: 504	TG: 41
Ying Liu [24]	2015	30	G1P0	32	Plasmapheresis	Compound Heterozygosity; (Glu242Lys and; Leu252VaL)	C/S	Fetal Distress	TG: 2160; Cholesterol: 670; Panc. Amylase: 132	TG: 420
Funda Gok [25]	2015	37		31	Insulin,; DF	IUMF	SVD		TG: 9742; Cholesterol: 705; Panc. Amylase: 570; Panc. Lipase: 319	TG: 556; Panc. Amylase: 107; Panc. Lipase: 77
Hae Rin Jeon [26]	2016	28	G1P0	23		IUMF,; Pancreatic Cells Necrotized,; Diabetic Ketoacidosis,; Metabolic Acidosis,; Cardiac Arrest, EX			TG: 10392; Cholesterol: 1006; Panc. Amylase: 1833; Panc. Lipase: 1863
Ioanna Polypathelli [27]	2017	38	G2P1	30	Heparin,; Fatty Acids,; Antibiotics		C/S	Resistant; Exaggerated; Thrombocytosis	TG: 14440; Cholesterol: 1600; Serum Amylase: 540	TG: 521
Tamanna Chibber [28]	2017	38		11		Cardiac Arrest, EX			TG: >1254; Cholesterol: 648; Panc. Lipase: 1079

BW: birth weight, G: gravida, P: parity, SVD: spontaneous vaginal delivery, BPP: biophysical profile, TPN: total parenteral nutrition, DF: double filtration apheresis, C/S: cesarean section, TG: triglyceride, ARDS: Adult Respiratory Distress Syndrome, and IUMF: Intra-Uterine Mort Fetus.
Triglyceride and total cholesterol units are calculated in mg/dL. Other units are converted to mg/dL.
Serum Amylase: normal range is between 30 and 110 (U/L) [11].
Pancreatic Amylase: normal range is between 17 and 115 (U/L) [11].
Pancreatic Lipase: normal range is between 13 and 60 U/L (U/L) [11].
TG: normal range is between 50 and 160 mg/dL (mg/dL) [11].
Cholesterol: normal range is between 130 and 230 (mg/dL) [11].
Highest values.
Lowest values.