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Case Reports in Obstetrics and Gynecology
Volume 2018 (2018), Article ID 8217296, 5 pages
https://doi.org/10.1155/2018/8217296
Case Report

Uterine Sarcoma Presenting with Sepsis from Clostridium perfringens Endometritis in a Postmenopausal Woman

1Department of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
2Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
3Division of Gynecologic Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA

Correspondence should be addressed to Ryan J. Spencer; ude.csiw@2recnepsjr

Received 8 January 2018; Accepted 12 March 2018; Published 16 April 2018

Academic Editor: Julio Rosa-e-Silva

Copyright © 2018 Mary J. Kao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. G. Tropé, V. M. Abeler, and G. B. Kristensen, “Diagnosis and treatment of sarcoma of the uterus. A review,” Acta Oncologica, vol. 51, no. 6, pp. 694–705, 2012. View at Publisher · View at Google Scholar
  2. M. M. Awad, A. E. Bryant, D. L. Stevens, and J. I. Rood, “Virulence studies on chromosomal α‐toxin and Θ‐toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of α‐toxin in Clostridium perfringens‐mediated gas gangrene,” Molecular Microbiology, vol. 15, no. 2, pp. 191–202, 1995. View at Publisher · View at Google Scholar · View at Scopus
  3. D. L. Stevens, J. Mitten, and C. Henry, “Effects of α and θ Toxins from Clostridium Perfringens on Human Polymorphonuclear Leukocytes,” The Journal of Infectious Diseases, vol. 156, no. 2, pp. 324–333, 1987. View at Publisher · View at Google Scholar · View at Scopus
  4. D. L. Stevens, R. W. Titball, M. Jepson, C. R. Bayer, S. M. Hayes-Schroer, and A. E. Bryant, “Immunization with the C-domain of α-toxin prevents lethal infection, localizes tissue injury, and promotes host response to challenge with Clostridium perfringens,” The Journal of Infectious Diseases, vol. 190, no. 4, pp. 767–773, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. I. Brook, “Microbiology and management of soft tissue and muscle infections,” International Journal of Surgery, vol. 6, no. 4, pp. 328–338, 2008. View at Publisher · View at Google Scholar
  6. G. B. Hart, R. C. Lamb, and M. B. Strauss, “Gas gangrene: I. A collective review,” Journal of Trauma - Injury Infection and Critical Care, vol. 23, no. 11, pp. 991–1000, 1983. View at Publisher · View at Google Scholar · View at Scopus
  7. T. F. Halpin and J. A. Molinari, “Diagnosis and management of Clostridium perfringens sepsis and uterine gas gangrene,” Obstetrical & Gynecological Survey , vol. 57, no. 1, pp. 53–57, 2002. View at Publisher · View at Google Scholar · View at Scopus
  8. R. P. Symonds and A. G. Robertson, “Clostridium welchii septicaemia after intrauterine caesium insertion,” British Medical Journal, vol. 1, no. 6115, pp. 754-755, 1978. View at Publisher · View at Google Scholar · View at Scopus
  9. R. Kurashina, H. Shimada, T. Matsushima, D. Doi, H. Asakura, and T. Takeshita, “Spontaneous uterine perforation due to clostridial gas gangrene associated with endometrial carcinoma,” Journal of Nippon Medical School, vol. 77, no. 3, pp. 166–169, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Braverman, A. Adachi, M. Lev-Gur et al., “Spontaneous clostridia gas gangrene of uterus associated with endometrial malignancy,” American Journal of Obstetrics & Gynecology, vol. 156, no. 5, pp. 1205–1207, 1987. View at Publisher · View at Google Scholar · View at Scopus
  11. C. S. Bryant, L. Perry, J. P. Shah, S. Kumar, and G. Deppe, “Life-threatening clostridial sepsis in a postmenopausal patient with degenerating uterine leiomyoma,” Case Reports in Medicine, vol. 2010, Article ID 541959, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. B. M. Kaufmann, J. M. Cooper, and P. Cookson, “Clostridium perfringens septicemia complicating degenerating uterine leiomyomas,” American Journal of Obstetrics & Gynecology, vol. 118, no. 6, pp. 877-878, 1974. View at Publisher · View at Google Scholar · View at Scopus