Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Obstetrics and Gynecology
Volume 2018, Article ID 8706738, 3 pages
https://doi.org/10.1155/2018/8706738
Case Report

Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure

1Maternal and Child Department, Careggi University Hospital Florence, Florence, Italy
2Infectious Disease Unit, Careggi University Hospital Florence, Florence, Italy

Correspondence should be addressed to Lucia Pasquini; ti.nit@iniuqsapaicul

Received 5 April 2018; Accepted 15 July 2018; Published 26 July 2018

Academic Editor: A. O. Awonuga

Copyright © 2018 Lucia Pasquini et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. L. McRalin, S. F. Bottoms, B. S. Dock, and N. B. Isada, “Epidemic syphilis: maternal factors associated with congenital infection,” American Journal of Obstetrics and Gynecology, vol. 170, no. 2, pp. 535–540, 1994. View at Google Scholar
  2. L. Newman, M. Kamb, S. Hawkes et al., “Global Estimates of Syphilis in Pregnancy and Associated Adverse Outcomes: Analysis of Multinational Antenatal Surveillance Data,” PLoS Medicine, vol. 10, no. 2, p. e1001396, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. M. De Santis, C. De Luca, I. Mappa et al., “Syphilis Infection during Pregnancy: Fetal Risks and Clinical Management,” Infectious Diseases in Obstetrics and Gynecology, vol. 2012, Article ID 430585, 5 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. C. A. Harter and K. Benirschke, “Fetal syphilis in the first trimester,” American Journal of Obstetrics & Gynecology, vol. 124, no. 7, pp. 705–711, 1976. View at Publisher · View at Google Scholar · View at Scopus
  5. L. Nathan, V. R. Bohman, P. J. Sanchez et al., “In utero infection with Treponema pallidum in early pregnancy,” Prenatal Diagnosis, vol. 17, no. 2, pp. 119–123, 1997. View at Google Scholar
  6. N. J. Fiumara, “Serologic responses to treatment of 128 patients with Late Latent Syphilis,” Sexually Transmitted Diseases, vol. 6, no. 4, pp. 243–246, 1979. View at Publisher · View at Google Scholar · View at Scopus
  7. G. B. Gomez, M. L. Kamb, L. M. Newman, J. Mark, N. Broutet, and S. J. Hawkes, “Untreated maternal syphilis and adverse outcomes of pregnancy: A systematic review and meta-analysis,” Bulletin of the World Health Organization, vol. 91, no. 3, pp. 217–226, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. J. M. Alexander, J. S. Sheffield, P. J. Sanchez, J. Mayfield, and G. D. Wendel Jr., “Efficacy of treatment for syphilis in pregnancy,” Obstetrics & Gynecology, vol. 93, no. 1, pp. 5–8, 1999. View at Publisher · View at Google Scholar · View at Scopus
  9. Centre for Disease Control and Prevention, “Sexually transmitted diseases treatment guidelines 2010,” MMWR, vol. 59, no. RR-12, 2010. View at Google Scholar
  10. L. M. Hollier, T. W. Harstad, P. J. Sanchez, D. M. Twickler, and G. D. Wendel, “Fetal Syphilis,” Obstetrics & Gynecology, vol. 97, no. 6, pp. 947–953, 2001. View at Publisher · View at Google Scholar
  11. M. W. F. Rac, S. N. Bryant, D. D. McIntire et al., “Progression of ultrasound findings of fetal syphilis after maternal treatment,” American Journal of Obstetrics & Gynecology, vol. 211, no. 4, pp. 426–426.e6, 2014. View at Publisher · View at Google Scholar · View at Scopus