Oncogenic Potential and Clinical Implications of Giant Endometrial Polyps: A Case Report and Literature Review

Table 1

Summary of reported cases of giant endometrial polyps.

Report	Patient age	Polyp size (cm)	Associated drugs	Management	Pathology
Çil et al. [1]; Malatya, Turkey	73	8 × 4 × 3	No	Hysteroscopic polypectomy	No hyperplasia, atypia, or malignancy
Moon et al.; Busan, Republic of Korea [7]	58	7.5 × 5.5 × 2.6	Tamoxifen	Total abdominal; hysterectomy	No hyperplasia, atypia, or malignancy
Nomikos et al. [8]; Piraeus, Greece	74	Diameter 8 cm	Tamoxifen	Total abdominal hysterectomy	Complex hyperplasia with atypia
Kutuk and Goksedef [9]; Amasya, Turkey	63	4.5 × 4 × 5.2	Raloxifene	Polypectomy under ultrasound guidance	No hyperplasia, atypia, or malignancy
Narin et al. [10]; Adana, Turkey	66	12 × 6 × 5	No	Total abdominal hysterectomy, BSO	No hyperplasia, atypia, or malignancy
Erdemoglu et al. [11]; Isparta, Turkey	55	10 × 6 × 3	Tamoxifen	Extraction of mass under general anesthesia	No hyperplasia, atypia, or malignancy
Caschetto et al. [12]	64	9 × 7 × 4.5	Tamoxifen	Total abdominal hysterectomy, BSO	Complex hyperplasia with atypia
Catania, Italy	67	8 × 6 × 3	Tamoxifen	Total abdominal hysterectomy, BSO	Simple hyperplasia, no atypia
Ünal et al. [13]; Antalya, Turkey	78	10 × 9	Phytoestrogens	Total abdominal hysterectomy	No hyperplasia, atypia, or malignancy
Meena et al. [14]; Delhi, India	65	8.5 × 1.5	No	Hysteroscopic polypectomy	Cystic hyperplasia without atypia
van Staalduinen et al.	70	9.1 × 5.2 × 7.1	No	Hysteroscopic polypectomy	No hyperplasia, atypia, or malignancy
New York, USA; (index cases)	66	8 × 6 × 5	No	Polypectomy/hysteroscopy	No hyperplasia, atypia, or malignancy