Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Oncological Medicine
Volume 2013, Article ID 684939, 4 pages
http://dx.doi.org/10.1155/2013/684939
Case Report

Primary Intrarenal Neuroblastoma with Hypertension and Disseminated Intravascular Coagulation

1Pediatric Congenital Hematologic Disorders Research Center, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran 15468-15514, Iran
2Department of Pediatric Hematology-Oncology, Mofid Children Hospital, Shariati Avenue, Tehran 15468-15514, Iran
3Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran 14194, Iran
4Molecular Immunology Research Center, School of Medicine, Tehran University of Medical Sciences, Tehran 14194, Iran
5Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran 14194, Iran
6Department of Pediatric Radiology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran 15468-15514, Iran
7Department of Pediatric Surgery, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran 15468-15514, Iran
8Department of Pediatric Pathology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran 15468-15514, Iran

Received 14 September 2013; Accepted 3 November 2013

Academic Editors: T.-W. Chang, M. Romkes, and Y. Shimizu

Copyright © 2013 Bibi Shahin Shamsian et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The primary intrarenal neuroblastoma (IRNB) is a rare condition. Intrarenal neuroblastoma typically results from direct renal invasion from an adrenal neuroblastoma, but true intrarenal neuroblastoma originates either sequestered adrenal rests during the fetal life or intrarenal sympathetic ganglia. Clinical, radiological, and pathological correlation is very essential for diagnosis and appropriate management of this type of unusual cases. The distinction of this rare tumor from Wilms’ tumor is an important challenge since both tumors have major differences in prognostic and therapeutic response. We present a 3-year-old boy of primary intrarenal neuroblastoma with extensive abdominal and mediastinal mass, persistent hypertension, and disseminated intravascular coagulation (DIC).