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Case Reports in Oncological Medicine
Volume 2015, Article ID 293802, 7 pages
Case Report

Primary Intracranial Melanoma with Early Leptomeningeal Spread: A Case Report and Treatment Options Available

1Department of Radiotherapy and Oncology, Square HospitalsLimited, Dhaka 1205, Bangladesh
2Department of Neurosurgery, Square HospitalsLimited, Dhaka 1205, Bangladesh
3Department of Pathology, Square HospitalsLimited, Dhaka 1205, Bangladesh

Received 20 May 2015; Revised 15 July 2015; Accepted 16 July 2015

Academic Editor: Jose I. Mayordomo

Copyright © 2015 Rajesh Balakrishnan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary CNS melanomas are rare and they constitute about 1% of all cases of melanomas and 0.07% of all brain tumors. These tumors are aggressive in nature and may metastasise to other organs. Till date less than 25 cases have been reported in the literature. The primary treatment for local intraparenchymal tumours is complete resection and/or radiotherapy and it is associated with good survival. However once there is disease spread to leptomeninges the overall median survival is around 10 weeks. In this case report we describe a primary intracranial melanoma without any dural attachment in 16-year-old boy who had radical excision of the tumor followed by radiotherapy who eventually had rapidly developed leptomeningeal disease and review the literature with a focus on the clinic pathological, radiological, and treatment options.