Primary Angiosarcoma of Urinary Bladder: 13th Reported Patient

Table 2

Histopathology and immunohistochemistry of all patients reported.

Patient	Stage	Histology	Immunophenotype	Author/year
1	N/A	Classic, focally with large dilated vascular spaces	N/A	Jungano, 1907 [10]
2	N/A	Classic, focally solid	N/A	Casal et al., 1970 [11]
3	At least lamina propria	Typical, “hobnail” cells	fVIII+, keratin−	Stroup and Chang 1987 [12]
4	T3	Typical	fVIII+, keratin−	Aragona et al., 1991 [13]
5	T2	Typical	N/A	Ravi, 1993 [14]
6	T3	Typical	fVIII+, CD34+	Navon et al., 1997 [15]
7	T4N0M0	Solid and primitive	fVIII+, CD31+, CD34+	Engel et al., 1998 [7]
8	TXN + M0	Solid, focally classic	fVIII−, CD34−, keratin−, CD31+	Schindler et al., 1999 [16]
9	Peritoneal surface	Solid, focally primitive	CD31+, CD43+, kertin−	Seethala et al., 2006 [8]
10	Muscularis	Typical	CD31+, CD34−, fVIII−	Kulaga et al., 2007 [17]
11	T4	Typical	fVIII+, CD31+, CD34+	Williams et al., 2008 [18]
12	MIBC	Typical	fVIII+, CD31+, CD34+	Warne et al., 2011 [2]
Current	MIBC	Typical	CD31+, CD34+, fVIII+, keratin−; cystitis cystica	Bahouth, 2015

Typical appearance includes anastomosing vascular channels. N/A: not available. MIBC = muscle-invasive bladder cancer.