|Biomarker and technology used are shown for each subtype, as percent of total cases. A total of EMPDs are also compared to MPD. Percent in each box refers to overexpression of target proteins except for PTEN*, RRM1*, and TS*, where the percent refers to underexpression of the target. Genes in which no mutation was found: ABL1, AKT1, ALK, ATM, BRAF, BRCA1, BRCA2, CDH1, c-KIT, cMET, CSF1R, CTNNB1, EGFR, ERBB2, ERBB4, FBXW7, FGFR1, FGFR2, FLT3, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, JAK2, JAK3, KDR, KRAS, MLH1, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, SMAD4, SMARCB1, SMO, STK11, TP53, and VHL.|
IHC, immunohistochemistry; ISH, fluorescence in situ hybridization.