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Case Reports in Oncological Medicine
Volume 2015, Article ID 907978, 6 pages
Case Report

A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist’s Point of View

1Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of Korea
2Department of Internal Medicine, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of Korea
3Department of Pathology, Ewha Womans University School of Medicine, Seoul 158-710, Republic of Korea

Received 6 January 2015; Accepted 20 April 2015

Academic Editor: Katsuhiro Tanaka

Copyright © 2015 Kyu Chan Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We here report a case of primary breast lymphoma (PBL). A 44-year-old woman presented with a painless mass in the right breast. Fine needle aspiration cytology and excisional biopsy were performed. Excisional biopsy revealed low grade lymphoma, which was subsequently confirmed with histopathology and diagnosed as diffuse large B-cell lymphoma (DLBCL). A chest computed tomography scan revealed a 3.5 cm sized breast mass with skin thickening and a small sized lymphadenopathy in the ipsilateral axilla. Radiation therapy including the right whole breast and ipsilateral axilla and supraclavicular lymph node was performed after the patient received four courses of R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone plus rituximab) chemotherapy. At the follow-up period of 42 months, the patient is surviving with no evidence of disease. No morbidities occurred in this patient during the follow-up period. We also briefly review the current practice pattern in PBL patients with DLBCL.