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Case Reports in Oncological Medicine
Volume 2017, Article ID 4537631, 4 pages
Case Report

Successful Outcome of Low-Dose S-1 Used to Treat Buccal Squamous Cell Carcinoma

1Department of Dentistry, Oral and Maxillofacial, Plastic and Reconstructive Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan
2Department of Dentistry and Oral Surgery, Shinjo Tokushukai Hospital, Yamagata, Japan

Correspondence should be addressed to Kazuyuki Yusa;

Received 19 April 2017; Accepted 30 May 2017; Published 18 July 2017

Academic Editor: Constantine Gennatas

Copyright © 2017 Kazuyuki Yusa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This case report describes an 86-year-old woman with dormant right buccal squamous cell carcinoma who was able to maintain a reasonable quality of life after being treated with oral low-dose S-1 (80 mg/day). The treatment regimen started in April 2014 and consisted of two weeks of S-1 followed by a one-week interval. The patient remains on this regimen while maintaining her quality of life and she has been under follow-up as an outpatient for 36 months. The outcomes for this patient indicated that low-dose S-1 is a valid anticancer therapy that may help maintain quality of life for some patients with incurable or dormant cancers.