Case Report

A Patient with Non-Hodgkin Lymphoma and Nonspecific Interstitial Pneumonia during Ibrutinib Therapy

Table 1

Pulmonary function test and relevant blood values (reference values in parentheses).

TestValue

One-second forced expiratory volume2.53 liters (81% of predicted)
Vital capacity3.17 liters (75% of predicted)
Total lung capacity (single breath)4.5 liters (62% of predicted)
FEV1/FVC ratio79.84% (106% of predicted)
Single-breath Krogh transfer factor for carbon monoxide1.05 mmol/(min kPa l) (84% of predicted)
NT-proBNP293 ng/l (<229)
Estimated GFR83 ml/min (>90)
Erythrocytes4.3 G/l (4.5–5.9)
Haemoglobin12.9 g/dl (14.0–17.5)
MCHC32 g/dl (33–36)
Thrombocytes108 G/l (139–335)
Neutrophils1.47 G/l, 32% (1.6–7.1, 40–75%)
Monocytes1.11 G/l, 24% (0.2–0.6, 4–11%)
IgG5.73 g/l (7–16)
IgG40.002 g/l (0.052–1.250)
IgM0.31 g/l (0.4–2.3)
Capillary pH7.46 (7.37–7.45)
Capillary pCO234 mmHg (35–46)
INF-gamma0.49 IU/ml (<0.35)
Relevant normal lab values includedANA, c-ANCA, p-ANCA, anti-CCP, rheumatoid factor, IgA, IgG1-3, IgE, creatinine, and lactate dehydrogenase