Malignant Pleural Mesothelioma with Marked Lymphatic Involvement: A Report of Two Autopsy Cases

Figure 2

(a) An axial chest CT scan showed extensive bronchovascular bundle and septal thickening, an upper lobe consolidative mass, and perilymphatic nodules in the left lung; these findings are consistent with the lymphangitic spread of the tumor. (b) A contrast-enhanced chest CT scan showing a left upper lobe consolidative mass, left-sided pleural effusion, and pleural thickening with mediastinal lymph node swelling. (c) The gross pathological findings of the lung and pleura at autopsy. The lung parenchyma is encased by tumor growth and the lymphatic spread of the tumor is observed. (d) A low-power magnification view of the pleural tumor. The tumor is composed of epithelioid and spindle cells (hematoxylin and eosin staining, ×100). (e) Low-power magnification of the pleural tumor. The lesion was histologically diagnosed as biphasic-type malignant pleural mesothelioma. The photomicrograph shows invasion of the lymphatic channels by the tumor (hematoxylin and eosin staining, ×100).

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