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Case Reports in Oncological Medicine
Volume 2017, Article ID 8247353, 4 pages
Case Report

Chronic Lymphocytic Leukemia as an Unusual Cause of Rapid Airway Compromise

1Department of Medicine, Hematology/Oncology, San Antonio Military Medical Center, Fort Sam Houston, TX, USA
2Department of Medicine, San Antonio Military Medical Center, Fort Sam Houston, TX, USA
3Department of Medicine, Hematology/Oncology, Eglin Hospital, Eglin AFB, FL, USA

Correspondence should be addressed to Adrian R. Bersabe; lim.liam@lim.ebasreb.r.nairda

Received 18 November 2016; Revised 1 March 2017; Accepted 2 March 2017; Published 15 March 2017

Academic Editor: Josep M. Ribera

Copyright © 2017 Adrian R. Bersabe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Chronic Lymphocytic Leukemia (CLL) is the most prevalent form of non-Hodgkin’s lymphoma (NHL) in Western countries predominantly affecting adults over the age of 65. CLL is commonly indolent in nature but can present locally and aggressively at extranodal sites. Although CLL may commonly present with cervical lymphadenopathy, manifestation in nonlymphoid regions of the head and neck is not well described. CLL causing upper airway obstruction is even more uncommon. We describe a case of a patient with known history of CLL and stable lymphocytosis that developed an enlarging lymphoid base of tongue (BOT) mass resulting in rapid airway compromise.