Response of Leptomeningeal Metastases in EGFR-Mutated Non-Small-Cell Lung Cancer to Afatinib in the Absence of Radiotherapy

Figure 1

T1 WI postgadobutrol administration sagittal slices. (a, d) Nodular enhancing lesions between 1 and 4 mm (arrows) at the centrum semiovale and left cerebellar hemisphere. Additional leptomeningeal enhancement was noticed at the pial surface of the left posterior quadrant (arrows). (b, e) Images obtained 7 months later. There is evident reduction in lesion size, and fewer leptomeningeal enhancement is noticed. (c, f) Images obtained 11 months from first study; no lesions or enhancement noted.

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