Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide Therapy

Table 1

Doxorubicin-ifosfamide (AI) therapy regimen.

	Drug	Volume/dose	Infusion time	Timing of administration
Days 1-2
Rp. 1	Saline	500 mL
	SHC	20 mL	4 h
Rp. 2	Saline	100 mL
	PH (day 1 only)	0.75 mg
	Dexamethasone	9.9 mg	15 min
Rp. 3	Saline	100 mL
	Doxorubicin	30 mg/m^2	2 h
Rp. 4	Saline	50 mL
	Mesna	400 mL/m^2	15 min
Rp. 5	Saline	500 mL
	Ifosfamide	2 g/m^2	4 h
Rp. 6	Saline	500 mL
	SHC	20 mL	4 h
Rp. 7	Saline	50 mL
	Mesna	400 mL/m^2	15 min	4 h after Rp. 5 administration
Rp. 8	Saline	500 mL
	SHC	20 mL	4 h
Rp. 9	Saline	50 mL
	Mesna	400 mL/m^2	15 min	8 h after Rp. 5 administration
Days 3-5
Rp. 1	Saline	500 mL
	SHC	20 mL	4 h
Rp. 2	Saline	100 mL
	Dexamethasone	9.9 mg	15 min
Rp. 3	Saline	50 mL
	Mesna	400 mL/m^2	15 min
Rp. 4	Saline	500 mL
	Ifosfamide	2 g/m^2	4 h
Rp. 5	Saline	500 mL
	SHC	20 mL	4 h
Rp. 6	Saline	50 mL
	Mesna	400 ml/m^2	15 min	4 h after Rp. 4 administration
Rp. 7	Saline	500 mL
	SHC	20 mL	4 h
Rp. 8	Saline	50 mL
	Mesna	400 mL/m^2	15 min	8 h after Rp. 4 administration

Abbreviations: Rp: recipe; SHC: sodium hydrogen carbonate, 8.4%; PH: palonosetron hydrochloride; h: hour; min: minute; AI: doxorubicin-ifosfamide.