Periampullary Metastases from Breast Cancer: A Case Report and Literature Review

Figure 1

Histologic sections of the duodenal major papilla tumor biopsy. (a) Hematoxylin and eosin, 10× amplification. (b) Hematoxylin and eosin, 40× amplification. (c) GATA-3 (IHC), 40× amplification. (d) ER (IHC), 40× amplification. (e) PR (IHC), 40× amplification. (f) HER2 (IHC), 40× amplification. Isolated tumor cells and tumor cells clustered in solid pattern were seen in the lamina propria of the duodenal mucosa. The tumor cells have pleomorphic nuclei with prominent nucleoli. IHC profiling was weakly positive for GATA-3 (c), strongly positive for HER2 (f), and negative for ER (d) and PR (e).

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