Acute Immune-Mediated Thrombocytopenia due to Oxaliplatin and Irinotecan Therapy

Figure 2

Detection of oxaliplatin-dependent platelet antibodies by flow cytometry. Platelets show high IgG binding when incubated with the patient’s serum in the presence of oxaliplatin (0.1 mg/mL) (light gray histogram on the right) compared to platelets incubated with buffer/no drug present (dark histogram in the center). The numbers above each histogram are the median fluorescence intensity (MFI) values.