Tropheryma whipplei Crystalline Keratopathy: Report of a Case and Updated Review of the Literature

Table 1

Review of cases reporting intraocular crystalline or crystalline-like deposits in the setting of Whipple’s disease.

Report	Age	Gender	Location of deposits	Diagnosis	Systemic findings at presentation
Current case	49	Male	Corneal endothelium	Heart valve and lymph node Bx	Arthralgias
Thaler et al. [9]	56	Male	Anterior chamber	Vitreous and duodenal PCR, duodenal Bx	Arthralgias
Williams et al. [18]	62	Male	Intraocular lens, capsular bag, iris	Vitreous and lens capsule biopsy and PCR	Arthritis; Fevers
Lim et al. [14]	23	Male	Preretinal or inner retinal	Vitreous PCR, jejunal Bx	Anemia, lymphadenopathy, diarrhea, malnutrition
Rickman et al. [20]	59	Female	Corneal endothelium	Vitreous biopsy, EM, PCR	Arthritis
Avila et al. [22]	33	Female	Subretinal	Small bowel biopsy showing PAS positive granules, EM	Fever, anorexia, diarrhea, weight loss

Bx: biopsy; PCR: polymerase chain reaction; EM: electron microscopy; PAS: periodic acid-Schiff.