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Case Reports in Ophthalmological Medicine
Volume 2013, Article ID 608253, 4 pages
Case Report

A Case of Medication-Resistant Acanthamoeba Keratitis Treated by Corneal Crosslinking in Turkey

1Department of Ophthalmology, Medipol University Hospital, 34800 Istanbul, Turkey
2Department of Ophthalmology, Cerrahpasa Medical Faculty of Istanbul University, 34800 Istanbul, Turkey

Received 15 November 2013; Accepted 5 December 2013

Academic Editors: K. Jayaraman and G. Kleinmann

Copyright © 2013 Goktug Demirci and Akif Ozdamar. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To report a case of medication-resistant acanthamoeba keratitis (AK) treated successfully by corneal crosslinking (CXL). Methods. A 26-year-old male with medication-resistant AK underwent a standard CXL procedure with local anesthesia, followed by central corneal epithelial debridement, application of riboflavin 0.1%, and UV-A irradiation. Results. The patient experienced a dramatic symptomatic improvement within 24 hours. At two months, keratitis was healed with a semitransparent paracentral scar that did not affect visual acuity. Conclusions. Our experience, considered in the context of recent studies, suggests that CXL may be an option for selected patients with medication-resistant AK and corneal melting. CXL allows patients to avoid emergency keratoplasty and experience rapid symptomatic relief.